The Largest High-throughput Sequencing Datasets
ITCM collects and analyze the largest uniform high-throughput sequencing datasets, including 1488
high-quality pharmacological transcription profiles of 496 active TCM ingredients. Notably, profiles
of 424 of TCM ingredients were firstly obtained.
Powerful Mining Strategies
ITCM innovatively deploys three mining strategies (signatureSearch, Proximity, Random Walk with
Restart) to explore the relationship between specific geneset (ingredient or disease) and
profiles/drugs/diseases.
Comprehensive TCM target Resource
ITCM integrates ten TCM-related databases, as well as the latest edition of the
Chinese/American/European Pharmacopoeia, manually curated TCM target , Japanese Kampo, and
official recommendation of formulae for COVID-19. All information has been cross-checked by
third-party academic resource.
High-quality Visualization
Each module of ITCM contain interactive and customizable charts, including barplots, dotpots,
volcano plots and heatmaps, relationship networks, radar maps, density plots, circle heatmap and
matrix dotplot.