I T C M

Integrated Traditional Chinese Medicine

The Largest High-throughput Sequencing Datasets

ITCM collects and analyze the largest uniform high-throughput sequencing datasets, including 1488 high-quality pharmacological transcription profiles of 496 active TCM ingredients. Notably, profiles of 424 of TCM ingredients were firstly obtained.

Powerful Mining Strategies

ITCM innovatively deploys three mining strategies (signatureSearch, Proximity, Random Walk with Restart) to explore the relationship between specific geneset (ingredient or disease) and profiles/drugs/diseases.

Comprehensive TCM target Resource

ITCM integrates ten TCM-related databases, as well as the latest edition of the Chinese/American/European Pharmacopoeia, manually curated TCM target , Japanese Kampo, and official recommendation of formulae for COVID-19. All information has been cross-checked by third-party academic resource.

High-quality Visualization

Each module of ITCM contain interactive and customizable charts, including barplots, dotpots, volcano plots and heatmaps, relationship networks, radar maps, density plots, circle heatmap and matrix dotplot.

Formulas

25,857

Herb+s

8,454

Ingredients

43,430

Targets

18,851

Diseases

11,180

Profile

1,488